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Afix

Generic Name: Cefixime
Manufacturer: Aristopharma

Afix (Cefixime) is a broad spectrum cephalosporin antibiotic of 3rd generation for oral administration. It is a bactericidal antibiotic and is stable to hydrolysis by many beta-lactamases. Cefixime kills bacteria by interfering the synthesis of the bacterial cell wall.

Indications

Afix is indicated for the treatment of the following acute infections caused by susceptible microorganisms:
  • Upper respiratory tract infections: Otitis media and other URTI where the causative organism is known or suspected to be resistant to other commonly used antibiotics.
  • Lower respiratory tract infection: Bronchitis.
  • Urinary tract infections: Cystitis, cystourethritis, pyelonephritis, typhoid fever & gonococcal urethritis.
  • Gonorrhea (Uncomplicated)
  • Typhoid fever

Possible Side Effects

Afix is generally well tolerated. The majority of adverse reactions observed in clinical trials was mild and self-limiting in nature. Gastro-intestinal disturbances: Diarrhoea (if severe diarrhoea occurs, Afix should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported. Central nervous system disturbances: Headache, dizziness, etc. Others: Hypersensitivity reactions which usually subsided upon discontinuation of therapy; infrequent and reversible haematological changes; elevation of serum amylase, etc.

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