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Generic name: Metformin Hydrochloride
Manufacturer: Aristopharma Ltd.

Metformin HCl is an oral hypoglycaemic agent. Metformin enhances insulin-stimulated glucose transport in skeletal muscle and increases peripheral glucose uptake due to improved insulin sensitivity. It decreases the hepatic glucose output as well as the rate of gluconeogenesis and stimulates glucosis. Metformin also facilitates the slower absorption of glucose from gastrointestinal tract.

Non-insulin dependent adult diabetes mellitus, when over weight or obesity not responding to dietary therapy.
Glucomet can be given alone as initial therapy or can be administered in combination with a sulfonylurea.
In insulin dependent diabetics, Glucomet may be given as an adjuvant to patients whose symptoms are not well controlled and who are often obese.

Drug interaction:
It may enhance the effects of anti-coagulants. As such patients receiving the two drugs concomitantly may need adjustment of the anti-coagulant dosage.


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