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Procef

Generic Name: Cefradine
Therapeutic Group: Anti Bacterial
Manufacturer: Incepta Pharmaceuticals Ltd.

Cefradine is a first generation cephalosporin antibiotic that works in a similar way to penicillin by inhibiting bacterial cell wall synthesis. It has a broad spectrum bactericidal activity against both gram-positive and gram-negative bacteria.

Indications

Procef (Cefradine) is indicated for the treatment of the following infections when caused by susceptible organisms:

The upper and lower respiratory tract infections: pharyngitis, sinusitis, otitis media, tonsillitis, laryngo-tracheo-bronchitis, acute and chronic bronchitis, lobar and chronic bronchopneumonia.

Urinary tract infections: cystitis, urethritis, pyelonephritis.

Skin and soft tissue infections: abscess, cellulitis, furunculosis and impetigo.

Surgical prophylaxis: Surgical procedures associated with high risk of disastrous consequences of infections. Procef is also of value where postoperative infections would be disastrous and where patients have a reduced host resistance to bacterial infection. Protection is best ensured by achieving adequate local tissue concentrations at the time when contaminations are likely to occur. Thus, Procef should be administered immediately prior to surgery and continued during the postoperative period.

Precautions

There is evidence of partial cross-allergenicity between penicillins and cephalosporins. Therefore Cefradine should be used with caution in patients with known hypersensitivity to penicillins.

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