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Rolac

Generic Name: Ketorolac Tromethamine
Manufacturer: Renata Limited

Rolac® contains Ketorolac Tromethamine which is a member of the pyrrolopyrrole group of nonsteroidal anti-inammatory drugs (NSAIDs) that exhibits analgesic, anti-inammatory and antipyretic activity. It has more pronounced analgesic activity than most NSAIDs. Ketorolac inhibits synthesis of prostaglandins and may be considered a peripherally acting analgesic.

INDICATIONS

  • Rolac® ampoules are indicated for the short- term management of moderate to severe acute postoperative pain.
  • Rolac® tablets are indicated for the short-term management of moderate postoperative pain.


SIDE EFFECTS/ADVERSE REACTIONS

  • Gastro-intestinal : Nausea, dyspepsia, gastro-intestinal pain, abdominal discomfort bowel changes, gastritis, diarrhoea eructation, constipation, atulence, fullness, melaena, peptic ulcer, rectal bleeding, stomatitis, vomiting, hemorrhage, perforation, pancreatitis.
  • Central nervous/musculoskeletal systems : Drowsiness, dizziness, headache, sweating, dry mouth, nervousness, paraesthesia, functional disorders, abnormal thinking, depression, euphoria, mental and sensory changes, convulsions, excessive thirst, inability concentrate, insomnia, stimulation, vertigo, abnormal taste and vision, myalgia, abnormal dreams, hallucinations, hyperkinesia, hearing loss, tinnitus, aseptic meningitis.
  • Renal : Increased urinary frequency, oliguria, acute renal failure, hyphonatraemia, hyperkalaemia, haemolytic uraemic syndrome, Flank pain (with or without haematuria), raised serum urea, creatinine and urinary symptoms & acute renal failure.
  • Cardiovascular/haematological : Flushing, bradycardia, pallor, purpura, thrombocytopenia, hypertension, inhibition of platelet aggregation & prolonged bleeding time, postoperative wound hemorrhage, and haematoma.
  • Respiratory : Dyspnoea, asthma, pulmonary edema. Dermatological : Pruritus, urticaria, Lyell's syndrome, Stevens Johnsons syndromre, exfoliative dermatitis, maculopapular rash.
  • Hypersensitivity reactions : Anaphylaxis, bronchospasm, laryngeal edema, hypotension, ushing and rash. Such reactions may occur in patients with or without known sensitivity to kerorolac or other NSAIDs.

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