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Generic name: Rupatadine
Manufacturer: Aristopharma Ltd.

Rupatadine is a long-acting, non-sedative antagonist of histamine H1-receptors. It also antagonizes the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction which leads to an increase in the vascular permeability and act as a mediator in the inflammatory process. Rupatadine possesses other anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli and inhibition of the release of cytokines, particularly of the tumor necrosis factor alpha (TNFa) in human mastocytes and monocytes.

Rupatadine is indicated for the symptomatic treatment of seasonal & perennial allergic rhinitis and urticaria.

The patient should take precaution in driving or managing machines.


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